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- Bioss
- bs-16799P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16799P |
| 英文名称 | KMT5C Antibody Blocking Peptide |
| 中文名称 | 组蛋白赖氨酸N-甲基5C封闭多肽 |
| 英文别名 | FLJ98627; Histone lysine N methyltransferase SUV420H2; KMT5C; Lysine N methyltransferase 5C; MGC2705; Su(var)4 20 homolog 2; SV422_HUMAN; Suppressor of variegation 4 20 homolog 2; Suv4 20h2; SUV420H2. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Methylation > Lysine methylation |
| 亚基 | Interacts with HP1 proteins CBX1, CBX3 and CBX5. Interacts with RB1 family proteins RB1, RBL1 and RBL2 (By similarity). {ECO:0000250}. |
| 亚细胞定位 | Nuclear. |
| 相似性 | Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily. |
| 功能 | KMT5C/SUV4-20h2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. KMT5C/SUV4-20h2 mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SUV420H2 and the related enzyme SUV420H1 (MIM 610881) function as histone methyltransferases that specifically trimethylate nucleosomal histone H4 (see MIM 602822) on lysine-20 (K20) (Schotta et al., 2004 [PubMed 15145825]).[supplied by OMIM, Dec 2009] |
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KMT5C Antibody Blocking Peptide(bs-16799P)-500ug
￥880
