TMEM121B Antibody Blocking Peptide(bs-9006P)-500ug

TMEM121B Antibody Blocking Pep

tide(bs-9006P)-500ug
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  • ¥880
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  • bs-9006P
  • 2025年10月16日
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      500ug

    产品编号bs-9006P
    英文名称TMEM121B Antibody Blocking Peptide
    中文名称猫眼综合征染色体候选基因6封闭多肽
    英文别名Cat eye syndrome chromosome region candidate 6; Cat eye syndrome chromosome region candidate 6 homolog (human); Cat eye syndrome chromosome region candidate 6 homolog; RGD1565302; AW048664; CECR6_HUMAN.
    纯化方法HPLC
    组织特异性Widely expressed, especially in adult heart, brain, prostate, testes, peripherical blood leukocytes and fetal brain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, although in some tissues it is associated with adenosine deaminase-binding protein. Adenosine deaminase degrades extracellular adenosine, which is toxic for lymphocytes. A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified. The cat eye syndrome critical region protein (CECR) family includes CECR1, CECR2, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9. The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development. CECR family members are widely expressed. Specifically, CECR1 has the highest expression in adult heart, lung, lymphoblasts and placenta. CECR2 is also involved in neurulation and chromatin remodeling. Mutations in the CECR2 gene result in neural tube defects.

     

     

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