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- Bioss
- bs-13651P
- 2025年10月16日
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500ug
| 产品编号 | bs-13651P |
| 英文名称 | SH2B3 Antibody Blocking Peptide |
| 中文名称 | 淋巴细胞特异性接头蛋白封闭多肽 |
| 英文别名 | IDDM20; Lymphocyte adapter protein; Lymphocyte specific adapter protein; Lymphocyte specific adapter protein Lnk; Lymphocyte-specific adapter protein Lnk; SH2B adapter protein 3; SH2B adaptor protein 3; Sh2b3; SH2B3_HUMAN; Signal transduction protein Lnk. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Adaptive Immunity > T Cells > Non-CD Signal Transduction > Adapters > Cytoplasmic Signal Transduction > Signaling Pathway > Lipid Signaling |
| 组织特异性 | Preferentially expressed by lymphoid cell lines. |
| 翻译后修饰 | Tyrosine phosphorylated by LCK. |
| 相似性 | Belongs to the SH2B adapter family. Contains 1 PH domain. Contains 1 SH2 domain. |
| 功能 | Links T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | APS (adapter molecule containing PH and SH2 domains), SH2-B and Lnk compose a family of adapter proteins, which contain a pleckstrin homology (PH) domain, an SH2 domain and a tyrosine phosphorylation site. Stimulation of B cell receptor (BCR) or T cell receptor (TCR) results in the phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of BCR, TCR and several substrates. APS, SH2-B and Lnk may bind to the ITAM domain of BCR and TCR. Lnk is tyrosine phosphorylated in response to TCR stimulation and APS has been shown to be tyrosine phosphorylated in response to BCR stimulation. |
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SH2B3 Antibody Blocking Peptide(bs-13651P)-500ug
￥880
