FAM110B Antibody Blocking Peptide(bs-15299P)-500ug

FAM110B Antibody Blocking Pept

ide(bs-15299P)-500ug
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  • ¥880
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  • bs-15299P
  • 2025年10月16日
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      500ug

    产品编号bs-15299P
    英文名称FAM110B Antibody Blocking Peptide
    中文名称8号染色体开放阅读框72封闭多肽
    英文别名Chromosome 8 open reading frame 72; F110B_HUMAN; Fam110b; Family with sequence similarity 110 member B; Protein FAM110B.
    纯化方法HPLC
    亚细胞定位Cytoplasm. Cytoplasm, cytoskeleton, centrosome.
    组织特异性Detected in thyroid, spleen and testis, and at lower levels in stomach, spinal cord, lymph node, trachea, adrenal gland, prostate, ovary and intestine. [SIMILARITY] Belongs to the FAM110 family.
    功能May be involved in tumor progression.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料FAM110B is a 370 amino acid protein, which contains several motifs that are conserved among FAM110 family members and a proline-rich region through which it probably binds proteins. Localized to the nucleus where they associate with centrosomes, FAM110A, FAM110B and FAM110C accumulate at the spindle poles during mitosis. Expression of FAM110B and FAM110C impairs cell cycle progression through G1 phase. FAM110B is expressed in testis, thyroid and spleen and is found at lower levels in ovary, adrenal gland, stomach, trachea, intestine, lymph node, spinal cord and prostate. The gene encoding FAM110B maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

     

     

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