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- bs-24328P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-24328P |
| 英文名称 | lamin B1 Antibody Blocking Peptide |
| 中文名称 | 核纤层蛋白B(细胞核膜标志物)封闭多肽 |
| 英文别名 | LMNB1_HUMAN; Lamin-B1; LMNB1; LMN2; LMNB; LMN; ADLD; MCPH26; |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cell Death > Apoptosis > Nucleus > Lamins Cell Biology > Apoptosis > Nucleus > Lamins Isotype/Loading Controls > Loading Controls > Lamin B1 - Nuclear Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Intermediate Filaments > Class V > Lamins Tags & Cell Markers > Subcellular Markers > Nucleus > Nuclear Envelope |
| 亚基 | Homodimer. Interacts with lamin-associated polypeptides IA, IB and 2. |
| 亚细胞定位 | Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side. |
| 翻译后修饰 | B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. |
| 相似性 | Belongs to the intermediate filament family. |
| 功能 | Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [provided by RefSeq, Oct 2010]. |
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lamin B1 Antibody Blocking Peptide(bs-24328P)-500ug
￥880
