Bak Antibody Blocking Peptide(bs-1284P)-500ug

Bak Antibody Blocking Peptide(

bs-1284P)-500ug
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  • bs-1284P
  • 2025年10月16日
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      500ug

    产品编号bs-1284P
    英文名称Bak Antibody Blocking Peptide
    中文名称Bcl-2同源拮抗剂封闭多肽
    英文别名Apoptosis Regulator Bak; BAK 1; BAK; BAK like; Bak NT; BAK1; Bcl 2 homologous antagonist/killer; Bcl 2 like 7 protein; Bcl2 homologous antagonist killer; Bcl2 like 7 Protein; BCL2-antagonist/killer 1; BCL2L7; CDN 1; CDN1; Cell death inhibitor 1; MGC117255; MGC3887; NBak; Pro apoptotic protein BAK; BAK_HUMAN; BAK_MOUSE.
    性状Lyophilized
    纯化方法HPLC
    研究领域

    Cell Biology > Apoptosis > Intracellular > Bcl2 Family

    亚基Belongs to the Bcl-2 family.
    亚细胞定位Mitochondrion membrane.
    组织特异性Expressed in a wide variety of tissues.
    相似性Belongs to the Bcl-2 family.
    功能In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]

     

     

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