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- Bioss
- bs-11470P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-11470P |
| 英文名称 | PLXNB3 Antibody Blocking Peptide |
| 中文名称 | 神经丛蛋白B3封闭多肽 |
| 英文别名 | Plexin B3; KIAA1206; PLEXB3; Plexin-B3; PLEXR; PLXB3_HUMAN; PLXN6; PLXNB3. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Growth and Development > Axonal Guidance Proteins |
| 亚基 | Interacts (via cytoplasmic domain) with RAC1 and ARHGDIA (By similarity). Binds MET and MST1R. Interacts (via cytoplasmic domain) with FSCN1. Interacts with RIT2/RIN. May form homodimers (via Sema domain). |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. Note=Colocalizes with RIT2/RIN at the plasma membrane. |
| 组织特异性 | Detected at very low levels in several fetal tissues. |
| 相似性 | Belongs to the plexin family. Contains 4 IPT/TIG domains. Contains 1 Sema domain. |
| 功能 | Receptor for SEMA5A. Plays a role in axon guidance, invasive growth and cell migration. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Plexins are a family of large, transmembrane receptors for multiple classes of semaphorins in vertebrates. They are widely expressed, and regions of their extracellular domain are homologus to both scatter factor receptors and semaphorin domains. Plexins may act as semaphorin receptors alone or in combination with neuropilins. Plexins are divided into four subfamilies designated plexin-A, -B, -C, and -D. Plexin-B1 and -B2 are both receptors for Sema4D, which stimulates axonal outgrowth of embryonic dorsal root ganglion neurons. . Plexin-B3 binds to Sema5A, which controls axon guidance and can initiate the intracellular signaling of the hepatocyte growth factor/scatter factor receptor Met. |
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PLXNB3 Antibody Blocking Peptide(bs-11470P)-500ug
￥880
