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- Bioss
- bs-16760P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16760P |
| 英文名称 | KLHDC4 Antibody Blocking Peptide |
| 中文名称 | KLHDC4蛋白封闭多肽 |
| 英文别名 | DKFZp434G0522; FLJ00104; Kelch domain containing protein 4. KLDC4_HUMAN |
| 纯化方法 | HPLC |
| 相似性 | Contains 6 Kelch repeats. |
| 功能 | Kelch proteins (and Kelch-like proteins) are proteins that have repeated kelch domains. Most Kelch proteins also have a BTB (defn) domain. Each kelch domain forms the blade of a propellar structure, with the repeated kelch domains forming a Beta-propellar. The structure of this Beta-propellar is known but the function is not characterised. KLHDC4 contains six Kelch repeats. There are three named isoforms. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | KLHDC4 is a 520 amino acid protein that contains six kelch repeats and exists as three alternatively spliced isoforms. The gene encoding KLHDC4 maps to human chromosome 16q24.2 and mouse chromosome 8 E1. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. |
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KLHDC4 Antibody Blocking Peptide(bs-16760P)-500ug
￥880
