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- bs-1395P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-1395P |
| 英文名称 | KLF6 Antibody Blocking Peptide |
| 中文名称 | 转染抑癌基因KLF6封闭多肽 |
| 英文别名 | Kruppel-like factor 6; B cell derived protein 1; BCD1; COPEB; Core promoter element-binding protein; CPBP; GC rich sites binding factor GBF; Krueppel-like factor 6; Proto-oncogene BCD1; Transcription factor Zf9; Zf9; CBA1; DKFZp686N0199; GBF; PAC1; ST12; KLF6_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families Epigenetics and Nuclear Signaling > Transcription > Domain Families > Krueppel like factor Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger Epigenetics and Nuclear Signaling > Transcription > Krueppel like factor Stem Cells > Hematopoietic Progenitors > Intracellular Molecules |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Highly expressed in placenta followed by spleen, thymus, prostate, testis, small intestine and colon. Weakly expressed in pancreas, lung, liver, heart and skeletal muscle. Also expressed in fetal brain, spleen and thymus. |
| 相似性 | Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers. |
| 功能 | Transcriptional activator (By similarity). Binds a GC box motif. Could play a role in B-cell growth and development. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | KLF6 is a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes. Two transcript variants encoding the same protein have been found for this gene. |
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KLF6 Antibody Blocking Peptide(bs-1395P)-500ug
￥880
