- ￥880
- Bioss
- bs-2104P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-2104P |
| 英文名称 | TNFAIP1 Antibody Blocking Peptide |
| 中文名称 | 肿瘤坏死因子α诱导蛋白1封闭多肽 |
| 英文别名 | tumor necrosis factor, alpha-induced protein 1-like; Tumor necrosis factor-alpha-induced protein 1; Tumor necrosis factor alpha induced protein 1 (endothelial); BACD2_HUMAN; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; BTB/POZ domain-containing protein TNFAIP1; endothelial; hBACURD2; Protein B12; tnfaip1; Tumor necrosis factor alpha induced protein 1; TNF-IP 1; TNF-IP-1; TNF-IP1. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Tags & Cell Markers > Cell Type Markers > Epi / Endo-thelial |
| 亚细胞定位 | Cytoplasm. Nucleus. Endosome. Colocalizes with RHOB in endosomes. |
| 翻译后修饰 | Phosphorylation at Ser-280 by CK2 facilitates the nucleus localization and increases interaction with PCNA. |
| 相似性 | Belongs to the BACURD family. Contains 1 BTB (POZ) domain. |
| 功能 | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. [provided by RefSeq, Jul 2008]. |
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TNFAIP1 Antibody Blocking Peptide(bs-2104P)-500ug
￥880
