TPSG1 Antibody Blocking Peptide(bs-12684P)-500ug

TPSG1 Antibody Blocking Peptid

e(bs-12684P)-500ug
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  • bs-12684P
  • 2025年10月16日
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      500ug

    产品编号bs-12684P
    英文名称TPSG1 Antibody Blocking Peptide
    中文名称膜类胰蛋白酶1封闭多肽
    英文别名gamma I; gamma II; lung tryptase; mast cell protease II; mast cell tryptase; pituitary tryptase; PRSS31; Serine protease 31; skin tryptase; TMT; Tpsg1; Transmembrane tryptase; trpA; TRYG1_HUMAN; Tryptase gamma (EC:3.4.21.-); tryptase gamma 1; tryptase gamma; Tryptase gamma heavy chain; tryptase gamma I; tryptase gamma II; Tryptase gamma light chain.
    纯化方法HPLC
    亚细胞定位Membrane.
    组织特异性Expressed in many tissues.
    相似性Belongs to the peptidase S1 family.
    Tryptase subfamily.
    Contains 1 peptidase S1 domain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008]

     

     

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