- ￥880
- Bioss
- bs-7897P
- 2025年10月16日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-7897P |
| 英文名称 | CDK13 Antibody Blocking Peptide |
| 中文名称 | 细胞分裂周期2样蛋白激酶5封闭多肽 |
| 英文别名 | CDC2 related protein kinase 5; CDC2-related protein kinase 5; CDC2L; CDK13; CDK13_HUMAN; cell division controller cholinesterase related; cell division cycle 2 like 5 (cholinesterase related cell division controller); cell division cycle 2 like 5; Cell division cycle 2 like protein kinase 5; Cell division cycle 2-like protein kinase 5; Cell division protein kinase 13; CHED; Cholinesterase related cell division controller; Cholinesterase-related cell division controller; cyclin dependent kinase 13; Cyclin-dependent kinase 13; hCDK13. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Kinases/Phosphatases > Cdks Epigenetics and Nuclear Signaling > Cell cycle > Kinases/Phosphatases > Cdks Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing > Splicing |
| 亚基 | Interacts with CCNL1 and CCNL2 (By similarity). Interacts with C1QBP. Interacts with HIV-1 Tat. |
| 亚细胞定位 | Nucleus speckle. |
| 组织特异性 | Expressed in fetal brain, liver, muscle and in adult brain. Also expressed in neuroblastoma and glioblastoma tumors. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. Contains 1 protein kinase domain. |
| 功能 | Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.Tissue specificity:Expressed in fetal brain, liver, muscle and in adult brain. Also expressed in neuroblastoma and glioblastoma tumors. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
CDK13 Antibody Blocking Peptide(bs-7897P)-500ug
￥880
