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- Bioss
- bs-11359P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11359P |
| 英文名称 | RIMS3 Antibody Blocking Peptide |
| 中文名称 | 神经元突触膜胞外分泌调节蛋白3封闭多肽 |
| 英文别名 | NIM 3; NIM3; Rab 3 interacting molecule 3; Regulating synaptic membrane exocytosis 3; Regulating synaptic membrane exocytosis protein 3; RIMS 3; RIMS-3; RIM 3; RIM3; RIM3 gamma; RIMS3; RIMS3_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Cell Type Marker > Neuron marker > Synapse marker Neuroscience > Neurotransmission > Secretory Vesicles > Regulation |
| 亚基 | Binds PPFIA3 (By similarity). Does not bind RAB3. |
| 亚细胞定位 | Cell junction, synapse. |
| 相似性 | Contains 1 C2 domain. |
| 功能 | RIMS3 belongs to a family of synaptic proteins that are essential for normal neurotransmitter release. It localizes primarily to neuronal dendrites and the postsynaptic densities, indicating that it may contribute to synapse transmission and plasticity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Rab 3, a neural/neuroendocrine-specific member of the Rab family, is involved in Ca2+-regulated exocytosis and functions in an inhibitory capacity, controlling the recruitment and pooling of secretory vesicles at the plasma membrane. The Rim (Rab 3 interacting molecule) family of proteins (Rim1, Rim2, Rim3 and Rim4) are multidomain adaptors that regulate Rab 3 activity and sub-sequent neurotransmitter release. Rim3, also known as RIMS3 (regulating synaptic membrane exocytosis 3) or NIM3, is a 308 amino acid member of the Rim family. Localized to the synapse and to cell junctions, Rim3 contains one C2 domain and is thought to play an important role in the regulation of synaptic membrane exocytosis. Rim3, a protein that may be phosphorylated upon DNA damage, is expressed throughout the body with highest levels present in brain tissue. |
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RIMS3 Antibody Blocking Peptide(bs-11359P)-500ug
￥880
