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- Bioss
- bs-13876P
- 2025年10月16日
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500ug
| 产品编号 | bs-13876P |
| 英文名称 | CFHL5 Antibody Blocking Peptide |
| 中文名称 | 补体因子H相关蛋白5封闭多肽 |
| 英文别名 | CFHL5; CFHR5; CFHR5D; Complement factor H-related 5; Complement factor H-related protein 5; factor H-related gene 5; factor H-related protein 5; FHR-5; FHR5; FHR5_HUMAN; FLJ10549; MGC133240; OTTHUMP00000034672. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > Complement > Alternative Pathway Immunology > Innate Immunity > Complement > Regulatory |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed by the liver and secreted in plasma. |
| 相似性 | Contains 9 Sushi (CCP/SCR) domains. |
| 功能 | Involved in complement regulation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010] |
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CFHL5 Antibody Blocking Peptide(bs-13876P)-500ug
￥880
