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- Bioss
- bs-11358P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11358P |
| 英文名称 | RIMBP2 Antibody Blocking Peptide |
| 中文名称 | 神经元突触膜结合蛋白2封闭多肽 |
| 英文别名 | RIM-BP2; RIMB2_HUMAN; RIMBP2; RIMS-binding protein 2. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with RIMS1, RIMS2, CACNA1D and CACNA1B, and potentially with other Ca(2+) channel alpha-1 isoforms (By similarity). |
| 亚细胞定位 | Cell membrane (By similarity). Cell junction, synapse (By similarity). Note=Synaptic plasma membrane (By similarity). |
| 组织特异性 | |
| 相似性 | Belongs to the RIMBP family. Contains 3 fibronectin type-III domains. Contains 3 SH3 domains. |
| 功能 | Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | RIMS-binding proteins (RIM-BPs) serve as adaptors during vesicle fusion and release by forming links between synaptic-vesicle fusion apparatuses and calcium channels. Specifically, RIM-BP2 (RIMS binding protein 2), also known as RBP2, is a 1,052 amino acid protein that links L-type Ca++ CP Alpha1D, N-type Ca++ CP Alpha1B, Rim1 and Rim2 during synaptic transmission. RIM-BP2 contains three fibronectin type-III domains and three SH3 domains, which are used to mediate binding to a proline-rich motifs. Existing as three alternatively spliced isoforms, RIM-BP2 is encoded by a gene that maps to human chromosome 12q24.33 and mouse chromosome 5 G1.3. |
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RIMBP2 Antibody Blocking Peptide(bs-11358P)-500ug
￥880
