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- bs-16688P
- 2025年10月16日
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500ug
| 产品编号 | bs-16688P |
| 英文名称 | IQCB1 Antibody Blocking Peptide |
| 中文名称 | NPHP5蛋白封闭多肽 |
| 英文别名 | IQ motif containing B1; IQ calmodulin binding motif containing protein 1; IQCB1; Nephrocystin 5; NPHP5; IQCB1_HUMAN; Nephrocystin-5 Nephrocystin5. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurotransmission > Calcium Signaling > Calmodulin / CaMK Neuroscience > Sensory System > Visual system Signal Transduction > Signaling Pathway > Calcium Signaling > Calmodulin Pathway |
| 亚细胞定位 | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:21565611}. Note=Localization to the centrosome depends on the interaction with CEP290. |
| 组织特异性 | Ubiquitously expressed in fetal and adult tissues. Localized to the outer segments and connecting cilia of photoreceptor cells. Up-regulated in a number of primary colorectal and gastric tumors. {ECO:0000269|PubMed:15723066, ECO:0000269|PubMed:16322217}. |
| 相似性 | Contains 4 IQ domains. |
| 功能 | Interacts with calmodulin. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009] |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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