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- Bioss
- bs-16688P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16688P |
| 英文名称 | IQCB1 Antibody Blocking Peptide |
| 中文名称 | NPHP5蛋白封闭多肽 |
| 英文别名 | IQ motif containing B1; IQ calmodulin binding motif containing protein 1; IQCB1; Nephrocystin 5; NPHP5; IQCB1_HUMAN; Nephrocystin-5 Nephrocystin5. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurotransmission > Calcium Signaling > Calmodulin / CaMK Neuroscience > Sensory System > Visual system Signal Transduction > Signaling Pathway > Calcium Signaling > Calmodulin Pathway |
| 亚细胞定位 | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:21565611}. Note=Localization to the centrosome depends on the interaction with CEP290. |
| 组织特异性 | Ubiquitously expressed in fetal and adult tissues. Localized to the outer segments and connecting cilia of photoreceptor cells. Up-regulated in a number of primary colorectal and gastric tumors. {ECO:0000269|PubMed:15723066, ECO:0000269|PubMed:16322217}. |
| 相似性 | Contains 4 IQ domains. |
| 功能 | Interacts with calmodulin. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009] |
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IQCB1 Antibody Blocking Peptide(bs-16688P)-500ug
￥880
