- ￥880
- Bioss
- bs-0716P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-0716P |
| 英文名称 | CIDEB Antibody Blocking Peptide |
| 中文名称 | 细胞死亡激活剂CIDE-B封闭多肽 |
| 英文别名 | cell death activator CIDE-B; Cell death activator CIDE B; Cell death inducing DFFA like effector B; CIDEB_HUMAN; cell death-inducing DFFA-like effector B; Cide-b. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 亚基 | Inhibited by DFFB. Interacts with DFFA and DFFB. |
| 组织特异性 | Highly expressed in liver and small intestine and, at lower levels, in colon, kidney and spleen. |
| 相似性 | Contains 1 CIDE-N domain. |
| 功能 | Activates apoptosis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as an inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE A and CIDE B were recently identified. CIDE contains a new type of domain termed CIDE N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE B induces apoptosis, which is inhibited by DFF45. CIDE B is a DFF45 inhibitable effector that promotes cell death and DNA fragmentation. CIDE B is expressed mainly in liver and small intestine and at lower levels in spleen, colon, kidney, peripheral blood lymphocytes, and bone marrow. |
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CIDEB Antibody Blocking Peptide(bs-0716P)-500ug
￥880
