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- 详细信息
- 技术资料
- 规格:
500ug
| 产品编号 | bs-7894P |
| 英文名称 | CDCA3 Antibody Blocking Peptide |
| 中文名称 | 细胞分裂周期相关蛋白3封闭多肽 |
| 英文别名 | CDCA 3; Cell division cycle associated 3; Cell division cycle associated protein 3; Gene rich cluster C8; Gene rich cluster protein C8; GRCC 8; GRCC8; MGC2577; TOME 1; TOME1; Trigger of mitotic entry 1; C8 antibody; Trigger of mitotic entry protein 1; CDCA3_HUMAN . |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Kinases/Phosphatases > Cdk Regulators Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > SCF Complex E3 Ligase Epigenetics and Nuclear Signaling > Cell cycle > Kinases/Phosphatases > Cdk Regulators Epigenetics and Nuclear Signaling > Cell cycle > Ubiquitin ligases |
| 亚基 | Protein modification; protein ubiquitination. [SUBUNIT] Interacts with SKP1. Part of a SCF (SKP1-cullin-F-box) protein ligase complex (By similarity). |
| 亚细胞定位 | Cytoplasm, cytosol (By similarity). |
| 翻译后修饰 | Ubiquitinated and degraded by the APC/C-Cdh1 complex (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 功能 | F-box-like protein which is required for entry into mitosis. Acts by participating in E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase (By similarity). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | CDCA3 (Cell division cycle associated 3) is an F-box-like protein which is required for entry into mitosis. It is associated with SKP1 as part of a SCF (SKP1-cullin-F-box) protein ligase complex, and is required for the ubiquitination and degradation of the CDK1 inhibitory tyrosine kinase WEE1 at G2/M phase. |
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CDCA3 Antibody Blocking Peptide(bs-7894P)-500ug
¥880





