CDCA3 Antibody Blocking Peptide(bs-7894P)-500ug

CDCA3 Antibody Blocking Peptid

e(bs-7894P)-500ug
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  • bs-7894P
  • 2025年10月16日
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      500ug

    产品编号bs-7894P
    英文名称CDCA3 Antibody Blocking Peptide
    中文名称细胞分裂周期相关蛋白3封闭多肽
    英文别名CDCA 3; Cell division cycle associated 3; Cell division cycle associated protein 3; Gene rich cluster C8; Gene rich cluster protein C8; GRCC 8; GRCC8; MGC2577; TOME 1; TOME1; Trigger of mitotic entry 1; C8 antibody; Trigger of mitotic entry protein 1; CDCA3_HUMAN .
    纯化方法HPLC
    研究领域

    Cell Biology > Cell Cycle > Kinases/Phosphatases > Cdk Regulators

    Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > SCF Complex E3 Ligase

    Epigenetics and Nuclear Signaling > Cell cycle > Kinases/Phosphatases > Cdk Regulators

    Epigenetics and Nuclear Signaling > Cell cycle > Ubiquitin ligases

    亚基Protein modification; protein ubiquitination. [SUBUNIT] Interacts with SKP1. Part of a SCF (SKP1-cullin-F-box) protein ligase complex (By similarity).
    亚细胞定位Cytoplasm, cytosol (By similarity).
    翻译后修饰Ubiquitinated and degraded by the APC/C-Cdh1 complex (By similarity).
    Phosphorylated upon DNA damage, probably by ATM or ATR.
    功能F-box-like protein which is required for entry into mitosis. Acts by participating in E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase (By similarity).
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料CDCA3 (Cell division cycle associated 3) is an F-box-like protein which is required for entry into mitosis. It is associated with SKP1 as part of a SCF (SKP1-cullin-F-box) protein ligase complex, and is required for the ubiquitination and degradation of the CDK1 inhibitory tyrosine kinase WEE1 at G2/M phase.

     

     

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