- ￥880
- Bioss
- bs-9505P
- 2025年10月16日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-9505P |
| 英文名称 | A2 Antibody Blocking Peptide |
| 中文名称 | α2巨球蛋白(α-2M)封闭多肽 |
| 英文别名 | A2M; A2MG_HUMAN; Alpha 2 M; Alpha 2M; Alpha-2-M; Alpha-2-macroglobulin; Alpha-2 Macroglobulin; Alpha 2-Macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; DKFZp779B086; FWP007; S863 7. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Blood > Serum Proteins Cell Biology > Proteolysis / Ubiquitin > Protease inhibitors > Other protease inhibitors |
| 亚基 | Homotetramer; disulfide-linked. |
| 亚细胞定位 | Secreted |
| 组织特异性 | Secreted in plasma |
| 相似性 | Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. |
| 功能 | Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq, Jul 2008]. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
A2 Antibody Blocking Peptide(bs-9505P)-500ug
￥880
