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- Bioss
- bs-43022P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
100ug/500ug/20ug
| 规格： | 100ug | 产品价格： | ￥2280.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥6880.0 |
| 规格： | 20ug | 产品价格： | ￥680.0 |
| 产品编号 | bs-43022P |
| 英文名称 | Recombinant human Azurocidin, His (HEK293) |
| 中文名称 | 重组人天青素/肝素结合蛋白 |
| 英文别名 | Azu 1; Azu1; CAP37; CAP7_HUMAN; cationic antimicrobial protein 37; Cationic antimicrobial protein CAP37; HBP; Heparin binding protein; Heparin-binding protein; HUMAZUR; Recombinant human Azurocidin, His (HEK293) |
| 中文别名 | 肝素结合蛋白; 阳离子抗菌蛋白37; 天青杀素; |
| 性状 | Lyophilized or Liqui |
| 纯化方法 | AC |
| 理论分子量 | 28.6 |
| 实际分子量 | 40 kDa |
| 浓度 | ＞0.5 mg/ml |
| 储存液 | PBS (pH7.4). |
| 研究领域 | Cardiovascular > Atherosclerosis > Vascular Inflammation > Leukocyte recruitment > Chemokines Immunology > Innate Immunity > Macrophage / Inflamm. Microbiology > Antimicrobial > Antibiotic Microbiology > Protein > Human Protein > Defensin |
| 亚基 | Monomer. |
| 亚细胞定位 | Cytoplasmic granule. Note=Cytoplasmic granules of neutrophils. Belongs to the peptidase S1 family. Elastase subfamily. Contains 1 peptidase S1 domain. |
| 相似性 | Belongs to the peptidase S1 family. Elastase subfamily.
Contains 1 peptidase S1 domain. |
| 功能 | This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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Recombinant human Azurocidin, His (HEK293)(bs-43022P)-100ug/500ug/20ug
￥680 - 6880
