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- Bioss
- bs-10723P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-10723P |
| 英文名称 | PRX Antibody Blocking Peptide |
| 中文名称 | 轴周蛋白PRX封闭多肽 |
| 英文别名 | PRX; CMT4F; KIAA1620; Periaxin; PRAX_MOUSE; Prx; L-Periaxin. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Neurodegenerative disease Neuroscience > Neurology process > Neurogenesis Neuroscience > Sensory System > Visual system |
| 亚基 | Interacts with SCN10A. Found in a complex with SCN10A. |
| 亚细胞定位 | Nucleus.Isoform 1: Cell membrane. Isoform 2: Cytoplasm. |
| 组织特异性 | Isoform 1 and isoform 2 are found in sciatic nerve and Schwann cells. |
| 相似性 | Belongs to the periaxin family. Contains 1 PDZ (DHR) domain. |
| 功能 | Seems to be required for maintenance of peripheral nerve myelin sheath. May have a role in axon-glial interactions, possibly by interacting with the cytoplasmic domains of integral membrane proteins such as myelin-associated glycoprotein in the periaxonal regions of the Schwann cell plasma membrane. May have a role in the early phases of myelin deposition. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy. [provided by RefSeq, Jul 2008] |
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PRX Antibody Blocking Peptide(bs-10723P)-500ug
￥880
