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- bs-11350P
- 2025年10月16日
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500ug
| 产品编号 | bs-11350P |
| 英文名称 | KIF1A Antibody Blocking Peptide |
| 中文名称 | 微管驱动蛋白家族成员1A封闭多肽 |
| 英文别名 | ATSV; Axonal transporter of synaptic vesicles; C2orf20; hUnc 104; hUnc-104; hunc104; Kif1a; KIF1A related protein; KIF1A_HUMAN; kinesin like protein; kinesin like protein KIF1A; Kinesin-like protein KIF1A; Microtubule based motor; Microtubule based motor KIF1A; Microtubule-based motor KIF1A; Unc 104 and KIF1A related protein; Unc 104; Unc-104- and KIF1A-related protein. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Cell Type Marker > Neuron marker > Synapse marker Neuroscience > Neurotransmission > Secretory Vesicles Neuroscience > Neurotransmission > Secretory Vesicles > SNAPs & SNAREs |
| 亚基 | Monomer. Interacts with PPFIA1 and PPFIA4 (By similarity). |
| 亚细胞定位 | Cytoplasm, cytoskeleton. Note=Expressed in distal regions of neurites. |
| 组织特异性 | Expressed in neurons. |
| 相似性 | Belongs to the kinesin-like protein family. Unc-104 subfamily. Contains 1 FHA domain. Contains 1 kinesin-motor domain. Contains 1 PH domain. |
| 功能 | Motor for anterograde axonal transport of synaptic vesicle precursors. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF1C is a member of the KIF1/Unc104 family of kinesin-like proteins, which are involved in the transport of mitochondria or synaptic vesicles in axons. The human KIF1A gene encodes a neuron-specific motor protein that delivers synaptic vesicle precursors to nerve terminals. KIF1A is a monomeric, globular molecule and has rapid anterograde motor activity (1.2 microns/s). KIF1A-mediated axonal transport plays a critical role in viability, maintenance and function of neurons, particularly mature neurons. KIF1A is associated with organelles that contain synaptic vesicle proteins such as synaptotagmin, synaptophysin and Rab 3A. |
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KIF1A Antibody Blocking Peptide(bs-11350P)-500ug
￥880
