SCP2 Antibody Blocking Peptide(bs-2014P)-500ug

SCP2 Antibody Blocking Peptide

(bs-2014P)-500ug
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  • ￥880
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  • bs-2014P
  • 2025年10月16日
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    北京博奥森生物技术有限公司
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      500ug

    产品编号bs-2014P
    英文名称SCP2 Antibody Blocking Peptide
    中文名称固醇携带蛋白2封闭多肽
    英文别名DKFZp686C12188; DKFZp686D11188; NLTP; Nonspecific lipid transfer protein; NSL TP; OTTHUMP00000010488; Propanoyl CoA C acyltransferase; SCP 2; SCP chi; SCP X; SCP2; SCPchi; SCPX; Sterol carrier protein 2; Sterol carrier protein X; NLTP_HUMAN.
    纯化方法HPLC
    研究领域

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism

    Signal Transduction > Metabolism > Lipid metabolism

    亚基Interacts with PEX5.
    亚细胞定位Cytoplasm. Mitochondrion. Note=Cytoplasmic in the liver and also associated with mitochondria especially in steroidogenic tissues.
    Isoform SCPx: Peroxisome. Note=Interaction with PEX5 is essential for peroxisomal import.
    Isoform SCP2: Mitochondrion (Probable).
    组织特异性Liver, fibroblasts, and placenta.
    相似性In the N-terminal section; belongs to the thiolase family.
    Contains 1 SCP2 domain.
    功能Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes two proteins: sterol carrier protein X(SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. [provided by RefSeq, Aug 2010]

     

     

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