KLRC1 Antibody Blocking Peptide(bs-2411P)-500ug

KLRC1 Antibody Blocking Peptid

e(bs-2411P)-500ug
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  • bs-2411P
  • 2025年10月16日
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      500ug

    产品编号bs-2411P
    英文名称KLRC1 Antibody Blocking Peptide
    中文名称NK细胞受体2A封闭多肽
    英文别名KLRC1; C lectin type II protein; CD159 antigen like family member A; CD159A; Killer cell lectin like receptor subfamily C member 1; MGC13374; MGC59791; Natural killer cell lectin; Natural killer group protein 2; NK cell receptor A; NKG2 1/B activating NK receptor; NKG2 A/B activating NK receptor; NKG2 A/B type II integral membrane protein; NKG2; NKG2A_HUMAN; NKG2-A/NKG2-B type II integral membrane protein; NKG2-A/B-activating NK receptor; NKG2A.
    性状Lyophilized
    纯化方法HPLC
    研究领域

    Immunology > Cell Type Markers > CD > NK Cells

    亚基Can form disulfide-bonded heterodimer with CD94.
    亚细胞定位Membrane; Single-pass type II membrane protein.
    组织特异性Natural killer cells.
    相似性Contains 1 C-type lectin domain.
    功能Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

     

     

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