- ￥880
- Bioss
- bs-13916P
- 2025年10月16日
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500ug
| 产品编号 | bs-13916P |
| 英文名称 | CHMP7 Antibody Blocking Peptide |
| 中文名称 | 染色质修饰蛋白CHMP7封闭多肽 |
| 英文别名 | Charged multivesicular body protein 7; CHMP family member 7; Chromatin modifying protein 7; CHMP7_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation |
| 亚基 | Interacts with CHMP4B, but not with VPS25. |
| 亚细胞定位 | Cytoplasm. Note: Diffused localization, with some punctate distribution, especially in the perinuclear area |
| 相似性 | Belongs to the SNF7 family. |
| 功能 | CHMP7 plays a role in the endosomal sorting pathway and is a component of the ESCRT III complex. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The charged multivesicular body proteins or chromatin modifying proteins, commonly designated CHMPs, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins. CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, II or III complexes. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), as well as required for the formation of these bodies. CHMP7 is an ESCRT-III-related protein that associates with CHMP4B. CHMP7 contains an SNF7 domain in the C-terminus and is most similar to CHMP6. CHMP7 also binds to the microtubule interacting and transport (MIT) domain of the deubiquitinating enzyme, UBPY. The overexpression of CHMP7 inhibits EGFR degradation. |
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CHMP7 Antibody Blocking Peptide(bs-13916P)-500ug
￥880
