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- Bioss
- bs-12654P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12654P |
| 英文名称 | DCLRE1A Antibody Blocking Peptide |
| 中文名称 | DNA交联修复基因SNM1封闭多肽 |
| 英文别名 | DCLRE1A; DNA cross link repair 1A; DNA cross link repair gene SNM1; PSO2. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > DNA Damage & Repair > DNA Damage Response |
| 亚基 | Binds constitutively to TP53BP1. Binds CDC27, which is itself a component of the anaphase promoting complex (APC). Binds PIAS1. |
| 亚细胞定位 | Nuclear. |
| 组织特异性 | Expressed in brain, heart, kidney, liver, pancreas, placenta and skeletal muscle. |
| 相似性 | Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family. |
| 功能 | May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a conserved protein that is involved in the repair of DNA interstrand cross-links. DNA cross-links suppress transcription, replication, and DNA segregation. The encoded protein is a regulator of the mitotic cell cycle checkpoint. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] |
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DCLRE1A Antibody Blocking Peptide(bs-12654P)-500ug
￥880
