Amphiphysin Antibody Blocking Peptide(bs-2409P)-500ug

Amphiphysin Antibody Blocking

Peptide(bs-2409P)-500ug
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  • bs-2409P
  • 2025年10月16日
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      500ug

    产品编号bs-2409P
    英文名称Amphiphysin Antibody Blocking Peptide
    中文名称神经元突触前膜蛋白封闭多肽
    英文别名Amphiphysin; Amp; AMPH 1; AMPH1; Amphiphysin (Stiff-Man syndrome with breast cancer 128kD autoantigen); Amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen); Amphiphysin I; CG8604; Damp; dAmph; Dmel\CG8604; HGNC:471; MGC49429; Stiff man syndrome with breast cancer 128kD autoantigen; Stiff man syndrome with breast cancer 128kDa autoantigen; AMPH_HUMAN.
    纯化方法HPLC
    研究领域

    Immunology > Immune System Diseases > Autoimmune

    Neuroscience > Cell Type Marker > Neuron marker > Synapse marker

    亚基Heterodimer with BIN1. Binds SH3GLB1 and AP2A2. Interacts with AP2B1.
    亚细胞定位Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.
    组织特异性Neurons, certain endocrine cell types and spermatocytes.
    相似性Contains 1 BAR domain.
    Contains 1 SH3 domain.
    功能May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Amphiphysin is associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants (Amphiphysin 1 and Amphiphysin 2) encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined.

     

     

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