CFC1 Antibody Blocking Peptide(bs-13873P)-500ug

CFC1 Antibody Blocking Peptide

(bs-13873P)-500ug
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  • ¥880
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  • bs-13873P
  • 2025年10月16日
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      500ug

    产品编号bs-13873P
    英文名称CFC1 Antibody Blocking Peptide
    中文名称内脏移位线管蛋白CFC1蛋白封闭多肽
    英文别名CFC 1; CFC1; CFC1_HUMAN; CFC1B; CR 1; Cripto 1; Cripto; Cripto FRL 1 cryptic family 1; CRYPTIC; Cryptic family 1; Cryptic family protein 1; Cryptic gene; Cryptic protein; DTGA2; FLJ77897; FRL 1; HTX2; MGC133213.
    纯化方法HPLC
    研究领域

    Cancer > Growth factors > EGF

    Developmental Biology > Embryogenesis > Axis formation and symmetry

    Signal Transduction > Growth Factors/Hormones > EGF

    亚细胞定位Cell membrane. Secreted. Does not exhibit a typical GPI-signal sequence. The C-ter hydrophilic extension of the GPI-signal sequence reduces the efficiency of processing and could lead to the production of an secreted unprocessed form. This extension is found only in primates.
    翻译后修饰N-glycosylated.
    相似性Contains 1 EGF-like domain.
    功能NODAL coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family, which are involved in signalling during embryonic development. Proteins in this family share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. The protein encoded by this gene is necessary for patterning the left-right embryonic axis. Mutations in this gene are associated with defects in organ development, including autosomal visceral heterotaxy and congenital heart disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

     

     

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