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500ug
| 产品编号 | bs-13873P |
| 英文名称 | CFC1 Antibody Blocking Peptide |
| 中文名称 | 内脏移位线管蛋白CFC1蛋白封闭多肽 |
| 英文别名 | CFC 1; CFC1; CFC1_HUMAN; CFC1B; CR 1; Cripto 1; Cripto; Cripto FRL 1 cryptic family 1; CRYPTIC; Cryptic family 1; Cryptic family protein 1; Cryptic gene; Cryptic protein; DTGA2; FLJ77897; FRL 1; HTX2; MGC133213. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Growth factors > EGF Developmental Biology > Embryogenesis > Axis formation and symmetry Signal Transduction > Growth Factors/Hormones > EGF |
| 亚细胞定位 | Cell membrane. Secreted. Does not exhibit a typical GPI-signal sequence. The C-ter hydrophilic extension of the GPI-signal sequence reduces the efficiency of processing and could lead to the production of an secreted unprocessed form. This extension is found only in primates. |
| 翻译后修饰 | N-glycosylated. |
| 相似性 | Contains 1 EGF-like domain. |
| 功能 | NODAL coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family, which are involved in signalling during embryonic development. Proteins in this family share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. The protein encoded by this gene is necessary for patterning the left-right embryonic axis. Mutations in this gene are associated with defects in organ development, including autosomal visceral heterotaxy and congenital heart disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
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CFC1 Antibody Blocking Peptide(bs-13873P)-500ug
¥880







