- ￥880
- Bioss
- bs-24046P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-24046P |
| 英文名称 | ECM1 Antibody Blocking Peptide |
| 中文名称 | 细胞外基质蛋白1封闭多肽 |
| 英文别名 | Secretory Component Glycoprotein; ECM 1; Ecm1; ECM1_Mouse; Extracellular matrix protein 1; Secretory component p85. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Immunoglobulins > Heavy Chain > IgA Immunology > Immunoglobulins > Heavy Chain > IgM Immunology > Immunoglobulins > Receptors Tags & Cell Markers > Cell Type Markers > Tumor Associated |
| 亚基 | Interacts (via C-terminus) with HSPG2 (via C-terminus). Interacts with EFEMP1/FBLN3 and LAMB3. Interacts with MMP9. |
| 亚细胞定位 | Secreted, extracellular space, extracellular matrix. |
| 组织特异性 | Expressed in breast cancer tissues. Little or no expression observed in normal breast tissues. Expressed in skin; wide expression is observed throughout the dermis with minimal expression in the epidermis. |
| 功能 | Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Extracellular matrix protein 1 (ECM1) This family consists of several eukaryotic extracellular matrix protein 1 (ECM1) sequences. ECM1 has been shown to regulate endochondral bone formation, stimulate the proliferation of endothelial cells and induce angiogenesis. Mutations in the ECM1 gene can cause lipoid proteinosis, a disorder which causes generalised thickening of skin, mucosae and certain viscera. Classical features include beaded eyelid papules and laryngeal infiltration leading to hoarseness. |
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ECM1 Antibody Blocking Peptide(bs-24046P)-500ug
￥880
