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- bs-1309P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-1309P |
| 英文名称 | Syndecan-1 Antibody Blocking Peptide |
| 中文名称 | 多配体蛋白聚糖1（CD138）封闭多肽 |
| 英文别名 | SDC1; SDC; SYND1; Syndecan I; SyndecanI; syndecan; Sdc1; Syndecan1; AA408134; AA409076; Sstn; syn-1; CD138; CD 138; CD-138; CD138 antigen; Heparan sulfate proteoglycan fibroblast growth factor receptor; SDC 1; Syndecan1 precursor; SDC1_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins Cancer > Invasion/microenvironment > ECM > Extracellular matrix Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism Metabolism > Types of disease > Cancer Neuroscience > Cell Adhesion Proteins > ECM Proteins Neuroscience > Cell Adhesion Proteins > Membrane Proteins Neuroscience > Cell Type Marker > Neuron marker > Synapse marker Neuroscience > Neurology process > Neurogenesis Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Proteins > Glucosaminoglycans Signal Transduction > Cytoskeleton / ECM > HSPGs Stem Cells > Hematopoietic Progenitors > Lymphoid > B Lymphocytic Lineage |
| 亚基 | Interacts with CDCP1. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. Secreted. Note=Shedding of the ectodomain produces a soluble form. |
| 翻译后修饰 | Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3. |
| 相似性 | Belongs to the syndecan proteoglycan family. |
| 功能 | Cell surface proteoglycan that bears both heparin sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008] |
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