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- bs-1175P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-1175P |
| 英文名称 | SHBG Antibody Blocking Peptide |
| 中文名称 | 性激素结合球蛋白封闭多肽 |
| 英文别名 | Sex Hormone Binding Globulin; ABP; Androgen binding protein; MGC126834; MGC138391; SBP; Sex steroid binding protein; SHBG; TEBG; Testis specific androgen binding protein; Testosterone binding beta globulin; Testosterone Estradiol Binding Globulin; Testosterone estrogen binding globulin; SHBG_HUMAN; Sex hormone-binding globulin; Sex steroid-binding protein; Testis-specific androgen-binding protein; Testosterone-estradiol-binding globulin; TeBG; Testosterone-estrogen-binding globulin. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Types of disease > Cancer Signal Transduction > Growth Factors/Hormones > Hormones Signal Transduction > Metabolism > Lipid metabolism |
| 亚基 | Homodimer. |
| 亚细胞定位 | Secreted . Note=In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis. |
| 组织特异性 | Isoform 1 and isoform 2 are present in liver and testis. |
| 翻译后修饰 | Variant Asn-356 contains one N-linked (GlcNAc...) at position 356. |
| 相似性 | Contains 2 laminin G-like domains. |
| 功能 | Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Sex hormone binding globulin (SHBG) is a glycoprotein synthesized by the liver. Circulating androgen and estrogen concentrations influence SHBG synthesis. Elevated testosterone, for example, causes SHBG synthesis to decrease, whereas high estrogen stimulates SHBG production. The regulation of SHBG synthesis, combined with SHBG's higher affinity for testosterone, impacts bioavailable testosterone levels. SHBG binds up to 98 percent of the steroid hormones in the blood including 5a-dihydrotestosterone (DHT), testosterone and androstenediol with particularly high affinity, and estradiol and estrone with slightly lower affinity. |
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SHBG Antibody Blocking Peptide(bs-1175P)-500ug
￥880
