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- bs-13842P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-13842P |
| 英文名称 | Centaurin beta 2 Antibody Blocking Peptide |
| 中文名称 | CENTB2蛋白封闭多肽 |
| 英文别名 | ACAP 2; ACAP2; ACAP2_HUMAN; ANK repeat and PH domain-containing protein 2; Ankyrin repeat; Arf GAP with coiled coil ANK repeat and PH domains 2; ARF GAP with coiled coil; Arf-GAP with coiled-coil; CENT B 2; Centaurin beta2; Centaurin-beta-2; CENTB 2; CENTB2; Cnt b2; Cnt-b2; Cntb2; KIAA0041; Pleckstrin homology domains 2; Similar to yeast ZINC FINGER PROTEIN GCS1. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Second Messenger > Nucleotide Messenger > GTP |
| 组织特异性 | Widely expressed. Highest level in lung. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Contains 3 ANK repeats. Contains 1 Arf-GAP domain. Contains 1 BAR domain. Contains 1 PH domain. |
| 功能 | GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The ADP-ribosylation factor (ARF) family of small GTP-binding proteins are involved in vesicular transport regulation and in controlling cytoskeletal organization and cell adhesion. These proteins mainly regulate membrane traffic. ACAP2 is a member of the centaurin GTPase-activating protein (GAP) family, which comprises a subset of ARF regulatory molecules that transduce PI 3-kinase activation into coordinated control of ARF-dependent pathways. ACAP1 and ACAP2 are both widely expressed in peripheral, tubular membranes and usually interact with each other in various tissues. GAP activity of both ACAP1 and ACAP2 is dependent upon phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2]. ACAP2 associates with ARF1 and ARF6. Overexpression of ACAP2 blocks the formation of ARF6-dependent protrusions. K1L is a protein required for growth of the Vaccinia Virus that interacts with the ankyrin repeats of ACAP2. |
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Centaurin beta 2 Antibody Blocking Peptide(bs-13842P)-500ug
￥880
