- ￥880
- Bioss
- bs-12597P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12597P |
| 英文名称 | PDIA6 Antibody Blocking Peptide |
| 中文名称 | 蛋白二硫异构酶A6封闭多肽 |
| 英文别名 | Endoplasmic reticulum protein 5; ER protein 5; ERP5; P5; Protein disulfide isomerase A6; Protein disulfide isomerase associated 6; Protein disulfide isomerase family A member 6; Protein disulfide isomerase P5; Protein disulfide isomerase related protein; Thioredoxin domain containing 7 (protein disulfide isomerase); Thioredoxin domain containing protein 7; TXNDC7. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Trafficking > ER Proteins |
| 亚基 | Part of a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. Interacts with MICA on the surface of tumor cells, leading to MICA disulfide bond reduction which is required for its release from tumor cells. Interacts with ITGB3 following platelet stimulation. |
| 亚细胞定位 | Endoplasmic reticulum. |
| 组织特异性 | Expressed in platelets (at protein level). |
| 相似性 | Belongs to the protein disulfide isomerase family. Contains 2 thioredoxin domains. |
| 功能 | May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Protein disulfide isomerase (PDIA6) ia an enzyme belonging to the protein disulfide isomerase family. Structurally, it contains 2 thioredoxin domains and its function is to catalyze the rearrangement of -S-S- bonds in proteins. |
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PDIA6 Antibody Blocking Peptide(bs-12597P)-500ug
￥880
