- ￥880
- Bioss
- bs-10633P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-10633P |
| 英文名称 | AS3MT Antibody Blocking Peptide |
| 中文名称 | 甲基转移酶cyt-19封闭多肽 |
| 英文别名 | 2310045H08Rik; CYT19; Arsenic (+3 oxidation state) methyltransferase; Arsenite methyltransferase; As3mt; AS3MT_HUMAN; C10ORF32; CYT19; Cyt19 protein; Hypothetical protein C10orf32; Methylarsonite methyltransferase; Methyltransferase cyt19; OTTHUMP00000020384; RP11-753C18.6; S adenosylmethionine arsenic (III) methyltransferase; S-adenosyl-L-methionine:arsenic(III) methyltransferase. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Other Antibodies > Oxidative Stress Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism Signal Transduction > Metabolism > Drug metabolism |
| 亚细胞定位 | Cytoplasm. |
| 相似性 | Belongs to the methyltransferase superfamily. |
| 功能 | Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Formation of methylated metabolites is a critical step in the metabolism of inorganic arsenic. Arsenite methyltransferase (cyt19) is localized to the cytoplasm and operates in the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate which is reduced to methylarsonite. Methylarsonite acts as a substrate and is converted into a much less toxic compound dimethylarsinate. cyt19 is highly expressed in liver. Inherited variation in cyt19 may contribute to variation in arsenic metabolism and possibly arsenic-dependent carcinogenesis in humans. |
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AS3MT Antibody Blocking Peptide(bs-10633P)-500ug
￥880
