mouse CD25 Rat mAb, APC conjugated(bsm-30157A-APC)-25T/50T/100T

mouse CD25 Rat mAb, APC conjug

ated(bsm-30157A-APC)-25T/50T/100T
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  • ¥760 - 1880
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  • bsm-30157A-APC
  • 2025年10月15日
  • 产品信息以Bioss网站为准
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    • 规格

      25T/50T/100T

    规格:25T产品价格:¥760.0
    规格:50T产品价格:¥1180.0
    规格:100T产品价格:¥1880.0
    产品编号bsm-30157A-APC
    英文名称mouse CD25 Rat mAb, APC conjugated
    中文名称APC标记小鼠CD25单克隆抗体
    英文别名Interleukin 2 receptor alpha chain; CD 25; CD25; CD25 antigen; IDDM10; IL 2 RA; IL 2 receptor alpha subunit; IL2 RA; IL-2RA; IL2R; IL2RA; IL2RAC; Interleukin 2 Receptor alpha; Interleukin 2 receptor alpha chain; Interleukin 2 receptor; Ly43; p55; T Cell Growth Factor Receptor; TAC Antigen; TCGFR; IL2RA_MOUSE.
    产品应用Flow-Cyt=10ul/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rat
    亚型Rat IgG1, λ
    性状Liquid
    纯化方法affinity purified by Protein G
    克隆类型Monoclonal
    理论分子量28 kDa
    实际分子量55kDa
    储存液0.01M PBS (pH7.4), 0.5% BSA, 0.02% Proclin300.
    研究领域

    Immunology > Adaptive Immunity > T Cells > CD

    Immunology > Innate Immunity > Cytokines > Interleukins

    亚基Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
    亚细胞定位Membrane; Single-pass type I membrane protein.
    相似性Contains 2 Sushi (CCP/SCR) domains.
    功能Receptor for interleukin-2.
    保存条件Store at 2-8℃. Protect from light. Avoid freezing.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. [provided by RefSeq, Jul 2020]

     

    应用推荐稀释比例
    {Flow-Cyt}{10ul/Test}

     

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