- ￥2980
- Bioss
- bs-4696R-HRP
- 2025年10月15日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
ENTPD2 Rabbit pAb, Biotin conjugated(bs-11515R-Bio)-100ul
￥2980
Synaptopodin Rabbit pAb, BF405 conjugated(bs-3633R-BF405)-100ul
￥2980human CD16 Mouse mAb, APC conjugated(bsm-30017M-APC)-25T/50T/100T
￥680
Sodium alginate Rabbit pAb(bs-4639R)-50ul/100ul/200ul
￥1180mouse CD11b Rat mAb, PE-Cy5 conjugated(bsm-30306A-PE-Cy5)-100T/25T/50T
￥1380
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-4696R-HRP |
| 英文名称 | AEV polyprotein Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的禽脑脊髓炎病毒AEV抗体 |
| 英文别名 | Avian encephalomyelitis virus; Genome polyprotein; RNA-directed RNA polymerase 3D-PO; P3D-POL; POLG_AEVCA; AEVgp1 aev polyprotein [ Avian encephalomyelitis virus ]. |
| 产品应用 | ELISA=1:5000-10000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from AEV polyprotein, RNA-directed RNA polymerase 3D-POL |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Protein VP2: Virion. Host cytoplasm (Potential).
Protein VP3: Virion. Host cytoplasm (Potential). Protein VP1: Virion. Host cytoplasm (Potential). Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Note=Probably localizes to the surface of intracellular membrane vesicles that are induced after virus infection as the site for viral RNA replication. These vesicles are derived from the endoplasmic reticulum. Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Note=Probably localizes to the surface of intracellular membrane vesicles that are induced after virus infection as the site for viral RNA replication. These vesicles are derived from the endoplasmic reticulum. May associate with membranes through a N-terminal amphipathic helix. Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Note=Probably localizes to the surface of intracellular membrane vesicles that are induced after virus infection as the site for viral RNA replication. These vesicles are derived from the endoplasmic reticulum. Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Note=Interacts with membranes in a complex with viral protein 3AB. Probably localizes to the surface of intracellular membrane vesicles that are induced after virus infection as the site for viral RNA replication. These vesicles are derived from the endoplasmic reticulum. |
| 翻译后修饰 | Specific enzymatic cleavages by the viral protease in vivo yield a variety of precursors and mature proteins. During virion maturation, non-infectious particles are rendered infectious following cleavage of VP0. This maturation cleavage is followed by a conformational change of the particle (By similarity). VPg is uridylylated by the polymerase and is covalently linked to the 5'-end of genomic RNA. This uridylylated form acts as a nucleotide-peptide primer for the polymerase (By similarity). |
| 相似性 | Belongs to the picornaviridae polyprotein family.
Contains 1 peptidase C3 domain. Contains 1 RdRp catalytic domain. Contains 1 SF3 helicase domain. |
| 功能 | Capsid proteins VP1, VP2, and VP3 form a closed capsid enclosing the viral positive strand RNA genome. All these proteins contain a beta-sheet structure called beta-barrel jelly roll. Together they form an icosahedral capsid (T=3) composed of 60 copies of each VP1, VP2, and VP3, with a diameter of approximately 300 Angstroms. VP1 is situated at the 12 fivefold axes, whereas VP2 and VP3 are located at the quasi-sixfold axes (By similarity). VP0 precursor is a component of immature procapsids. The N-terminal domain of VP0, protein VP4, is needed for the assembly of 12 pentamers into the icosahedral structure. Unlike other picornaviruses, AEV VP4 may not be myristoylated (By similarity). Protein 2B and 2BC precursor affect membrane integrity and cause an increase in membrane permeability (By similarity). Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity). Protein 3A, via its hydrophobic domain, serves as membrane anchor (By similarity). Protein 3B is covalently linked to the 5'-end of both the positive-strand and negative-strand genomic RNAs. It acts as a genome-linked replication primer (By similarity). Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity). RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity). |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | 禽脑脊髓炎病毒AEV是由细小RNA病毒科(Picornaviridae)、肠病毒属(Enterovirus)的禽脑脊髓炎病毒(AEvirus,AEV)引起的,以主侵幼鸡中枢神经系统引起非化脓性脑炎为主要病理特征的一种病毒性传染病。本病呈世界性分布.对禽类可造成很大威胁。 |
| 应用 | 推荐稀释比例 |
| {ELISA} | {1:5000-10000} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
AEV polyprotein Rabbit pAb, HRP conjugated(bs-4696R-HRP)-100ul
￥2980
