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- 应用范围:
产品信息以Bioss网站为准
- 规格:
50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-10815R |
| 英文名称 | FMDV VP1 Rabbit pAb |
| 中文名称 | 口蹄疫病毒VP1抗体 |
| 英文别名 | foot and mouth disease virus; Foot-and-mouth disease virus-type O; Foot-and-mouth disease virus-type Asia 1; Foot-and-mouth disease virus-type Asia 1; Foot-and-mouth disease virus-type C; VP1 protein; FMDV Polyprotein(VP1 protein). |
| 产品应用 | WB=1:500-2000, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | FMDV |
| 抗体来源 | Rabbit |
| 免疫原 | Recombinant FMDV Asia1 VP1 (His tag) |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 240 kDa |
| 浓度 | 1mg/ml |
| 储存液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 亚细胞定位 | Host cytoplasm. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The foot-and-mouth disease virus (FMDV) is the pathogen that causes foot-and-mouth disease. It is a picornavirus, the prototypical member of the Aphthovirus genus. The disease, which causes vesicles (blisters) in the mouth and feet of bovids, suids, ovids, caprids and other cloven-hoofed animals is highly infectious and a major plague of animal farming. The virus particle (25-30 nm) has an icosahedral capsid made of protein, without envelope, containing a single strand of ribonucleic acid (RNA) containing a positive encoding of its genome. When the virus comes in contact with the membrane of a host cell, it binds to a receptor site and triggers a folding-in of the membrane. Once the virus is inside the host cell, the capsid dissolves, and the RNA gets replicated, and translated into viral proteins by the cell's ribosomes using a cap-independent mechanism driven by the internal ribosome entry site element. The foot-and-mouth disease virus occurs in seven major serotypes: O, A, C, SAT-1, SAT-2, SAT-3, and Asia-1. These serotypes show some regionality, and the O serotype is most common. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {ELISA} | {1:5000-10000} |

Lane 1: Recombinant FMDV VP1 protein, Sumo & His(bs-10815P)
Lane 2: Recombinant FMDV VP1 (type O) protein, Sumo & His(bs-41028P)
Lane 3: Recombinant FMDV VP1 (type O) protein, Sumo & His(bs-41049P)
Primary: Anti-FMDV VP1 (bs-10815R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 240 kDa
Observed band size: 45 kDa
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文献和实验[IF={{ 2.6 }}] {Weijun Zeng. et al.Foot-and-mouth disease virus-like particle vaccine incorporating dominant T and B cell epitopes: enhanced immune response in piglets with CD154 molecules.frontiers in veterinary science.2025 Feb 19:12:1540102.} {Western blot} {}
for a plant virus, tobacco mosaic virus. In 1963, Anderer (1 ) demonstrated that rabbit antibodies to an isolated hexapeptide fragment from the virus-coat protein coupled to bovine serum albumm would neutralize the infectious vn-us in culture. Two years later
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