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ERLEC1 Antibody Blocking Pepti

de(bs-14625P)-500ug
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  • 2025年10月16日
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      500ug

    产品编号bs-14625P
    英文名称ERLEC1 Antibody Blocking Peptide
    中文名称内质网凝集素1封闭多肽
    英文别名C2orf30; CL24936; CL2508; endoplasmic reticulum lectin 1; ER lectin; erlectin 1; RP23 20N14.5; ERLEC_HUMAN; XTP3 B; XTP3 transactivated gene B protein; XTP3 transactivated protein B; XTP3B; XTP3TPB.
    纯化方法HPLC
    研究领域

    Signal Transduction > Protein Trafficking > Chaperones > Other Chaperones

    Signal Transduction > Protein Trafficking > ER Proteins

    亚基May form a complex with OS9, HSPA5, SYVN1, and SEL1L with which it interacts directly. Interacts (via PRKCSH 2 domain) with KREMEN2 (when glycosylated). Interacts with HSPA5.
    亚细胞定位Endoplasmic reticulum lumen.
    翻译后修饰Isoform 1 and isoform 2 are N-glycosylated.
    相似性Contains 2 PRKCSH domains.
    功能ERLEC1 is a probable lectin that binds selectively to improperly folded lumenal proteins. ERLEC1 may function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a resident endoplasmic reticulum (ER) protein that functions in N-glycan recognition. This protein is thought to be involved in ER-associated degradation via its interaction with the membrane-associated ubiquitin ligase complex. It also functions as a regulator of multiple cellular stress-response pathways in a manner that promotes metastatic cell survival. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 21. [provided by RefSeq, Aug 2011]

     

     

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