ELOVL1 | SSC1 Ab Blocking Peptide(bs-14571P)-500ug产品图

ELOVL1 | SSC1 Ab Blocking Pept

ide(bs-14571P)-500ug
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  • ¥880
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  • bs-14571P
  • 2026年10月10日
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      500ug

    产品编号bs-14571P
    英文名称ELOVL1 Antibody Blocking Peptide
    中文名称ELOVL1蛋白封闭多肽
    英文别名3 keto acyl CoA synthase ELOVL1; 3-keto acyl-CoA synthase ELOVL1; CGI 88; Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 1; Elongation of very long chain fatty acids like 1; Elongation of very long chain fatty acids protein 1; ELOV1_HUMAN; ELOVL 1; ELOVL FA elongase 1; ELOVL fatty acid elongase 1; ELOVL1; Ssc1; very long chain 3 oxoacyl CoA synthase 1; Very-long-chain 3-oxoacyl-CoA synthase 1.
    纯化方法HPLC
    研究领域

    Cardiovascular > Lipids / Lipoproteins > Fatty Acids > Synthesis

    Metabolism > Pathways and Processes > Redox metabolism > Fatty acid oxidation

    Signal Transduction > Metabolism > Lipid metabolism

    亚基Interacts with LASS2, TECR and HSD17B12.
    亚细胞定位Endoplasmic reticulum membrane; Multi-pass membrane protein.
    组织特异性Ubiquitous.
    相似性Belongs to the ELO family.
    功能Condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids (VLCFAs). Exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Elongation of very long chain fatty acid-like (ELOVL) proteins 1-6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 1 (ELOVL1), also referred to as Ssc1, is the human homolog of the yeast ELO3 protein. It is expressed in a variety of tissues and at especially high levels in stomach, skin, intestine, kidney and lung. ELOVL1 participates in the elongation of very long chain saturated and monounsaturated fatty acids of up to 26 carbons and may be required for the development of a barrier in epithelial cells and skin. ELOVL1 is also important for the formation of Myelin in the central nervous system. Impaired ELOVL1 activity may be associated with disorders of sphingolipid metabolism.

     

     

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