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- bs-17284P
- 2025年10月16日
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500ug
| 产品编号 | bs-17284P |
| 英文名称 | CLEC11A Antibody Blocking Peptide |
| 中文名称 | 干细胞生长因子SCGF封闭多肽 |
| 英文别名 | SCGF beta; C type lectin domain family 11 member A; C type lectin superfamily member 3; C-type lectin domain family 11 member A; C-type lectin superfamily member 3; CLC11_HUMAN; CLEC11A; CLECSF3; LSLCL; Lymphocyte secreted C type lectin; Lymphocyte secreted C-type lectin; lymphocyte secreted long form of C type lectin; p47; Stem cell growth factor; stem cell growth factor lymphocyte secreted C type lectin. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > Cytokines |
| 亚细胞定位 | Cytoplasm. Secreted. |
| 组织特异性 | Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver. |
| 翻译后修饰 | O-glycosylated. Probably sulfated on the O-glycans. |
| 相似性 | Contains 1 C-type lectin domain. |
| 功能 | Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SCGF is a cytokine for primitive hematopoietic progenitor cells and exhibits species-specific activity. It is predominantly expressed in proliferating chondrocytes, bone marrow cells, the periosteum and the perichondrium of skeletal tissues. SCGF contains an N-terminal Arg-Gly-Asp triplet (RGD triplet), leucine zipper domains, a C-terminal C-type lectin domain and numerous potential glycosylation sites. It has burst-promoting activity and granulocyte/macrophage colony-promoting activity in vitro. SCGF is directly correlated to granulocyte recovery following stem cell transplantation and thus can be an indicator of hematopoietic recovery following stem cell transplantation. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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