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- bs-41310P
- 2026年10月10日
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20ug/100ug/500ug
| 规格： | 20ug | 产品价格： | ￥580.0 |
|---|---|---|---|
| 规格： | 100ug | 产品价格： | ￥1880.0 |
| 规格： | 500ug | 产品价格： | ￥5680.0 |
| 产品编号 | bs-41310P |
| 英文名称 | Recombinant human Smoothened protein, His |
| 中文名称 | 重组跨膜蛋白Smoothened |
| 英文别名 | Gx; Gx protein; SMO; SMOH; Smoothened homolog (Drosophila); Smoothened homolog; Smoothened homolog precursor (SMO) (Gx protein); SMO_HUMAN; Recombinant human Smoothened protein, His |
| 性状 | Lyophilized or Liqui |
| 纯化方法 | AC |
| 理论分子量 | 22.3 |
| 实际分子量 | 28 kDa |
| 浓度 | ＞0.5 mg/ml |
| 储存液 | 20mM Tris-HCl (pH8.0). |
| 研究领域 | Neuroscience > Neurology process > Neurogenesis Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Signal Transduction > Adapters > Transmembrane Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR Stem Cells > Signaling Pathways > Hedgehog > Surface Molecules |
| 亚基 | Interacts with ARRB2. Interacts with KIF7. |
| 亚细胞定位 | Membrane. |
| 相似性 | Belongs to the G-protein coupled receptor Fz/Smo family. Contains 1 FZ (frizzled) domain. |
| 功能 | G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia._x000D_ |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010]Function : G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia. |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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rHu SMO Protein, His(bs-41310P)-20ug/100ug/500ug
￥580 - 5680
