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- Bioss
- bs-3755P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-3755P |
| 英文名称 | CRKL Antibody Blocking Peptide |
| 中文名称 | 接头蛋白CrkL封闭多肽 |
| 英文别名 | Crk L; Crk like protein; Crkol; HGNC:2363; Oncogene CrkL; V crk avian sarcoma virus CT10 oncogene homolog like; V crk sarcoma virus CT10 oncogene homolog avian like; CRKL_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Oncoproteins/suppressors > Oncoproteins Cancer > Signal transduction Epigenetics and Nuclear Signaling > Transcription > Cancer susceptibility > Proto-oncogenes Epigenetics and Nuclear Signaling > Transcription > Domain Families > HLH / Leucine Zipper > Leucine Zipper Neuroscience > Neurology process > Neural Signal Transduction Neuroscience > Neurotransmission > Intracellular Signaling > Kinases Signal Transduction > Adapters > Cytoplasmic |
| 亚基 | Interacts with INPP5D/SHIP1. Interacts with DOCK2 and EPOR. Interacts with phosphorylated CBLB and IRS4. |
| 相似性 | Belongs to the CRK family.
Contains 1 SH2 domain. Contains 2 SH3 domains. |
| 功能 | May mediate the transduction of intracellular signals. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Crkl is a 34kDa adaptor protein which has been shown to activate the RAS and JUN kinase signalling pathways and transforms fibroblasts in a RAS dependant manner. Crkl is a substitute of BCR ABL tyrosine kinase. In addition, Crkl has oncogenic potential. |
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CRKL Antibody Blocking Peptide(bs-3755P)-500ug
￥880
