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500ug
| 产品编号 | bs-3655P |
| 英文名称 | PAEP Antibody Blocking Peptide |
| 中文名称 | 胎盘蛋白14封闭多肽 |
| 英文别名 | Placental protein 14; alpha uterine protein; Pregnancy-associated endometrial alpha-2 globulin; GD; GdA; GdF; GdS; Glycodelin; Glycodelin F; Glycodelin S; PAEG; PAEP; PAEP protein; PEG; PEP; PP14; Pregnancy associated endometrial alpha 2 globulin; Progestagen associated endometrial protein (placental protein 14); Progestagen associated endometrial protein; Progesterone associated endometrial protein; MGC138509; MGC142288; PAEP_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Tags & Cell Markers > Cell Type Markers > Other Cell Types |
| 亚基 | Homodimer. |
| 亚细胞定位 | Secreted. |
| 翻译后修饰 | At least two differentially glycosylated forms are found. Glycodelin-A (GdA) (amniotic fluid) with contraceptive and immunosuppressive activities and glycodelin-S (Gds) (seminal plasma) whose role is not yet known. The gender-specific glycosylation may serve to regulate key process involved in human reproduction. |
| 相似性 | Belongs to the calycin superfamily. Lipocalin family. |
| 功能 | This protein is, quantitatively, the main protein synthesized and secreted in the endometrium from mid-luteal phase of the menstrual cycle and during the first semester of pregnancy. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined. [provided by RefSeq, Jul 2008]. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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