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FOCAD Antibody Blocking Peptid

e(bs-16158P)-500ug
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  • ¥880
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  • bs-16158P
  • 2025年10月16日
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      500ug

    产品编号bs-16158P
    英文名称FOCAD Antibody Blocking Peptide
    中文名称Focadhesin蛋白封闭多肽
    英文别名FOCAD; FOCAD_HUMAN; Focadhesin; KIAA1797.
    纯化方法HPLC
    亚基Interacts with VCL.
    亚细胞定位Membrane. Cell junction; focal adhesion. Colocalizes with VCL in astrocytes.
    组织特异性Ubiquitous. High expression in brain followed by testis, muscle, pancreas, heart, ovary, small intestine, placenta, prostate, thymus, kidney, colon, liver, lung, spleen and leukocytes. Expression is reduced in most glioblastomas and all glioblastoma cell lines.
    功能Potential tumor suppressor in gliomas.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The KIAA1797 gene product has been provisionally designated KIAA1797 pending further characterization.

     

     

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