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- Bioss
- bs-20726P
- 2025年10月16日
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500ug
| 产品编号 | bs-20726P |
| 英文名称 | FUT4 Antibody Blocking Peptide |
| 中文名称 | α-(1,3)-岩藻糖基转移酶 4封闭多肽 |
| 英文别名 | FUT4_HUMAN; Alpha-(1,3)-fucosyltransferase 4; 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase; EC:2.4.1.152; ELAM-1 ligand fucosyltransferase; Fucosyltransferase 4; Fucosyltransferase IV (Fuc-TIV; FucT-IV); Galactoside 3-L-fucosyltransferase; ELFT; FCT3A; LeX; CD15; FUTIV; SSEA-1; SSEA1; FUC-TIV; |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Tumor immunology > CD markers Developmental Biology > Embryogenesis > Embryonic stem cells > Surface molecules Immunology > Cell Type Markers > CD > Adhesion Stem Cells > Embryonic Stem Cells > Surface Molecules Stem Cells > Endothelial Progenitors > Endothelial Markers Stem Cells > Hematopoietic Progenitors > Hematopoietic Stem Cells > Human Lineage Negative Tags & Cell Markers > Cell Type Markers > Tumor Associated Tags & Cell Markers > Subcellular Markers > Organelles > Golgi |
| 亚细胞定位 | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi. |
| 组织特异性 | Highest expression in stomach and colon. It is also expressed in the lung, testis, uterus, small intestine and to a lesser extent in spleen, and ovary. Present in trace amounts in brain, thymus, heart, smooth muscle, kidney and bone marrow. Not found in liver, salivary gland and pancreas. |
| 相似性 | Belongs to the glycosyltransferase 10 family. |
| 功能 | May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq]. |
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FUT4 Antibody Blocking Peptide(bs-20726P)-500ug
￥880
