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- 2025年10月16日
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500ug
| 产品编号 | bs-17192P |
| 英文名称 | IZUMO1 Antibody Blocking Peptide |
| 中文名称 | IZUMO1蛋白封闭多肽 |
| 英文别名 | IZUM1_HUMAN; IZUMO; Izumo sperm egg fusion 1; Izumo sperm-egg fusion protein 1; Izumo1; MGC34799; OBF; Oocyte binding/fusion factor; Sperm specific protein izumo; Sperm-specific protein izumo. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Reproduction > Fertilisation |
| 亚基 | Monomer, homodimer and homooligomer. Interacts with IZUMO1R/JUNO (By similarity). |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Sperm-specific (at protein level). Detectable on sperm surface only after the acrosome reaction. |
| 翻译后修饰 | N-glycosylated. Glycosylation is not essential for fusion and for proper protein trafficking in sperm. Phosphorylated. |
| 相似性 | Belongs to the Izumo family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. |
| 功能 | Involved in the fertilization process. May be involved in the fusion of the sperm with the egg. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma membrane binding and fusion (Inoue et al., 2005 [PubMed 15759005]).[supplied by OMIM, Mar 2008] |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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