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DSU/MREG Antibody Blocking Pep

tide(bs-14433P)-500ug
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  • ¥880
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  • bs-14433P
  • 2025年10月16日
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      500ug

    产品编号bs-14433P
    英文名称DSU/MREG Antibody Blocking Peptide
    中文名称视杆细胞相关蛋白MREG封闭多肽
    英文别名Dilute suppressor; Dilute suppressor protein homolog; DSU; FLJ10116; MREG_HUMAN; Melanoregulin; MGC90296; MREG; OTTHUMP00000206794; OTTHUMP00000206795; OTTHUMP00000206796; WDT 2; WDT2; Whn dependent transcript 2.
    纯化方法HPLC
    亚基Interacts with PRPH2.
    亚细胞定位Apical cell membrane; Peripheral membrane protein.
    组织特异性Expressed in photoreceptor cells (at protein level).
    相似性Belongs to the melanoregulin family.
    功能Plays a role in the incorporation of pigments into hair. May function in membrane fusion and regulate the biogenesis of disk membranes of photoreceptor rod cells.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The photoreceptor rod cell that is responsible for vision under conditions of low light consists of stacked arrays of disk membranes that make up its outer segment portion. Regulated by complex biochemical mechanisms, the rod outer segment is under constant renewal as new disks form at the base. MREG is thought to play a role in membrane fusion and in regulating the biogenesis of disk membranes of photoreceptor rods. MREG interacts with RDS (also known as Peripherin-2), a photoreceptor specific tetraspanin protein that is required to maintain normal cell structure during the renewal process of membrane fusion. MREG is 214 amino acids in length, is expressed in photoreceptor cells and and is expressed as two isoforms due to alternative splicing.

     

     

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