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- bs-13488P
- 2025年10月16日
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500ug
| 产品编号 | bs-13488P |
| 英文名称 | GOLPH3 Antibody Blocking Peptide |
| 中文名称 | 高尔基体磷蛋白3封闭多肽 |
| 英文别名 | Coat protein GPP34; FLJ90675; Golgi peripheral membrane protein 1, 34 kDa; Golgi phosphoprotein 3 (coat protein); Golgi phosphoprotein 3; GOLP3_HUMAN; Golph3; GPP34; MIDAS; Mitochondrial DNA absence factor. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Trafficking > Golgi Proteins Signal Transduction > Protein Trafficking > Vesicle Transport > Coat Proteins Tags & Cell Markers > Subcellular Markers > Organelles > Golgi |
| 亚基 | Homodimer. Interacts with VPS35. |
| 亚细胞定位 | Cell membrane. Endosome. Cytoplasm. Golgi apparatus > Golgi stack membrane. Mitochondrion intermembrane space. |
| 组织特异性 | Detected in muscle fibers of patients with mitochondrial diseases; not detected in normal muscle fibers. |
| 翻译后修饰 | Phosphorylated. |
| 相似性 | Belongs to the GOLPH3/VPS74 family. |
| 功能 | Involved in modulation of mTOR signaling. Involved in the regulation of mitochondrial lipids, leading to increase of mitochondrial mass. Potential oncogene. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. GOLPH3L (golgi phosphoprotein 3-like), also known as GPP34R, is a 285 amino acid cytoplasmic protein that localizes to the Golgi apparatus. Belonging to the GOLPH3/VPS74 family, GOLPH3L may have a regulatory role in Golgi trafficking. GOLPH3L is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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