Parvalbumin Ready-To-Use IHC Kit(IHC0672)-50T

Parvalbumin Ready-To-Use IHC K

it(IHC0672)-50T
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  • IHC0672
  • 2025年10月15日
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      50T

    产品编号 IHC0672
    英文名称 Parvalbumin Ready-To-Use IHC Kit
    中文名称 细小清蛋白即用型免疫组化试剂盒
    英文别名 D22S749; PALB1; Pva; PVALB; MGC116759; Parvalbumin alpha; PRVA_HUMAN; parvalbumin; PV
    产品应用 IHC-P

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 Mouse, Rat
    相似性 Belongs to the parvalbumin family.
    功能 In muscle, parvalbumin is thought to be involved in relaxation after contraction (By similarity). It binds two calcium ions (PubMed:15122922, PubMed:39584689).
    保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
    背景资料 Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.

     

    应用 推荐稀释比例

     

    Immunohistochemical analysis of paraffin embedded Rat cerebellum tissue slide using IHC0672 (Parvalbumin Kit).
    Immunohistochemical analysis of paraffin embedded Mouse cerebellum tissue slide using IHC0672 (Parvalbumin Kit).

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