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- IHC0527M
- 2025年10月15日
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- 规格：
50T
| 产品编号 | IHC0527M |
| 英文名称 | Mouse LY75 Ready-To-Use IHC Kit |
| 中文名称 | 小鼠淋巴细胞抗原75（CD205）即用型免疫组化试剂盒 |
| 英文别名 | CD205; CLEC13B; DEC-205; GP200-MR6; LY-75; LY75 |
| 产品应用 | IHC-P Not yet tested in other applications. |
| 交叉反应 | Mouse |
| 亚细胞定位 | Membrane |
| 组织特异性 | Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells. |
| 翻译后修饰 | N-glycosylated. |
| 功能 | Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes |
| 保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 背景资料 | CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia. |
| 应用 | 推荐稀释比例 |
Immunohistochemical analysis of paraffin embedded Mouse spleen tissue slide using IHC0527M (Mouse LY75 Kit).
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Mouse LY75 Ready-To-Use IHC Kit(IHC0527M)-50T
￥3200
